Publications
BG Medicine's founders and employees have authored numerous publications for peer reviewed journals, books and other scholarly records. Below are some selected titles authored by BG's personnel. Selected titles link to the author's web site where you can find the articles.
Van der Greef, J and McBurney, R.N
Rescuing Drug Discovery and Drug Development: In Vivo Systems Pathology and Systems Pharmacology
Nature Reviews Drug Discovery, December, 2005, 4, 1-7.
Smilde AK, Jansen JJ, Hoefsloot HC, Lamers RJ, van der Greef J, Timmerman ME.
ANOVA-Simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data.
Bioinformatics. Jul, 2005, 1;21(13):3043-8.
Oresic M, Clish CB, Davidov EJ, Verheij E, Vogels J, Havekes LM, Neumann E, Adourian A, Naylor S, van der Greef J, Plasterer T.
Phenotype characterisation using integrated gene transcript, protein and metabolite profiling.
Appl Bioinformatics. 2004, 3(4):205-17
Davidov E, Clish CB, Oresic M, Meys M, Stochaj W, Snell P, Lavine G, Londo TR, Adourian A, Zhang X, Johnston M, Morel N, Marple EW, Plasterer TN, Neumann E, Verheij E, Vogels JT, Havekes LM, van der Greef J, Naylor S.
Methods for the differential integrative omic analysis of plasma from a transgenic disease animal model.
OMICS. 2004, 8(4):267-88
Jansen JJ, Hoefsloot HC, Boelens HF, van der Greef J, Smilde AK.
Analysis of longitudinal metabolomics data.
Bioinformatics Oct. 2004, 12;20(15):2438-46.
Morel NM, Holland JM, van der Greef J, Marple EW, Clish C, Loscalzo J, Naylor S.
Primer on medical genomics. Part XIV: Introduction to systems biology--a new approach to understanding disease and treatment.
Mayo Clin Proc. May 2004, 79(5):651-8. Review.
Van der Greef J, Stroobant P, van der Heijden R.
The role of analytical sciences in medical systems biology.
Curr Opin Chem Biol. 2004, Oct;8(5):559-65.
Clish CB, Davidov E, Oresic M, Plasterer TN, Lavine G, Londo T, Meys M, Snell P, Stochaj W, Adourian A, Zhang X, Morel N, Neumann E, Verheij E, Vogels JT, Havekes LM, Afeyan N, Regnier F, van der Greef J, Naylor S.
Integrative Biological Analysis of the APOE*3-Leiden Transgenic Mouse.
OMICS - A Journal of Integrative Biology. 2004, 8, 3-13.
J. van der Greef, R. van der Heijden, E.R. Verheij.
The Role of Mass Spectrometry in Systems Biology: Data Processing and Identification Strategies in Metabolomics. In: Advances in Mass Spectrometry, Volume 16. Edited by Ashcroft AE, Brenton G, Monaghan JJ. Amsterdam: Elsevier Science:
2004, 16: Chapter 9 :145-165
J. van der Greef, ER Verheij, J Vogels, R van der Heijden, E Davidov, S Naylor
The role of metabolomics in Systems Biology, a new vision for drug discovery and development Chapter 10 in "Metabolic Profiling: Its role in biomarker discovery and gene function analysis" George G. Harrigan and Royston Goodacre ((Eds)).
Kluwer Academic Publishing, Boston MA, USA, 2003, p170-198
Jan van der Greef, PhD, et al.
Chapter 10: "The Role of Metabolomics in System Biology".
Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis.
(Kluwer Academic Publishers, Boston, MA., 2003).
Harrigan, G. and Goodacre, R. , Editors.
Eric Neumann, PhD, et al.
Knowledge Assembly for the Life Sciences.
Drug Discovery Today. 2002, Vol. 7 No. 20 (Suppl.)
Stephen Valentine, PhD, David Clemmer, PhD, et al.
Multidimensional Separations of Complex Peptide Mixtures: A Combined High-performance Liquid Chromatography/Ion Mobility/Time-of-Flight Mass Spectrometry Approach.
International Journal of Mass Spectrometry. 2001, 212, 97-109.
David Clemmer, PhD, et al.
Assessment of Purity and Screening of Peptide Libraries by Nested Ion Mobility-TOFMS: Identification of RNase S-protein Binders.
Analytical Chemistry. 2001, 73, 424-433.
David Clemmer, PhD, et al.
ESI/Ion Trap/Ion Mobility/Time-of-Flight Mass Spectrometry for Rapid and Sensitive Analysis of Biomolecular Mixtures.
Analytical Chemistry. 1999, 71, 291-301.
Fred Regnier, PhD, et al.
A Signature Peptide Approach to Detecting Proteins in Complex Mixtures.
Journal of Chromatography A. 1999, 870, 295-313.
